Juventus entered the match without a defeat since May 15, when they lost 1-0 to Parma.

But the golden run Antonio Conte's side had embarked on looked like coming to an end at the San Siro after Antonio Nocerino gave the hosts the lead on 15 minutes.

Nocerino's effort from distance took a deflection and wrong-footed Juventus goalkeeper Gianluigi Buffon.

Conte brought Simone Pepe and Mirko Vucinic off the bench in the second half to increase his side's attacking options but it was another substitute in Matri who would make the telling impact.

Pepe provided the assist and the forward did the rest, side-footing home for his 10th goal of the season with just seven minutes to play.

Juventus' Chilean midfielder Arturo Vidal was given a straight red card on 89 minutes in a heated end to an exciting match.

Milan top the league by one point, with Juventus sitting second.

The day's other match saw Rodrigo Palacio strike twice in the final 20 minutes to earn Genoa a point in a 2-2 draw with Parma.

Goals to Massimo Gobbi and Sergio Floccari before the hour mark handed Parma the lead but the Argentine forward rescued a draw for his side off his own boot.

Firstly, he tapped in the rebound after seeing his penalty saved with 12 minutes remaining.

Palacio's second came six minutes into stoppage time as he netted his ninth goal in as many matches for Genoa.

Parma had defender Alessandro Lucarelli sent off just moments after in a heated finish to the match.